Catálogo de publicaciones - libros

The sea urchin has been an instructive animal for studies of gene regulation in development, morphogenesis, and cell migration. This is in part due to their convenient external development, their ease in culturing, and their marvelous transparency that makes them optically accessible for many developmental and cellular events. The embryo displays a multitude of complex movements and features, but involves relatively few cells (< 500 during gastrulation). The embryo is resilient to micromanipulation studies whereby cells or portions of tissues may be readily microinjected, transplanted, or photo-ablated to test mechanistically the crafting of the embryo. The whole genome project, its correlated EST identification and arrays (see http://sugp.caltech.edu), combined with the simple technology of introducing exogenous genes, reporters, mRNA, morpholinos or over-expressed proteins prove to be a powerful combination of capabilities with the nearly limitless number of embryos (several million per adult female) make the biochemistry and molecular biology of manipulated embryos readily available.[] Finally, its status as a basal deuterostome, representing an early branch in the evolution of vertebrates, makes its molecular and cellular changes ripe for comparison in understanding the origin of body plan, embryonic mechanism, gene regulation and function.

The sea urchin has been an instructive animal for studies of gene regulation in development, morphogenesis, and cell migration. This is in part due to their convenient external development, their ease in culturing, and their marvelous transparency that makes them optically accessible for many developmental and cellular events. The embryo displays a multitude of complex movements and features, but involves relatively few cells (< 500 during gastrulation). The embryo is resilient to micromanipulation studies whereby cells or portions of tissues may be readily microinjected, transplanted, or photo-ablated to test mechanistically the crafting of the embryo. The whole genome project, its correlated EST identification and arrays (see http://sugp.caltech.edu), combined with the simple technology of introducing exogenous genes, reporters, mRNA, morpholinos or over-expressed proteins prove to be a powerful combination of capabilities with the nearly limitless number of embryos (several million per adult female) make the biochemistry and molecular biology of manipulated embryos readily available.[] Finally, its status as a basal deuterostome, representing an early branch in the evolution of vertebrates, makes its molecular and cellular changes ripe for comparison in understanding the origin of body plan, embryonic mechanism, gene regulation and function.

The sea urchin has been an instructive animal for studies of gene regulation in development, morphogenesis, and cell migration. This is in part due to their convenient external development, their ease in culturing, and their marvelous transparency that makes them optically accessible for many developmental and cellular events. The embryo displays a multitude of complex movements and features, but involves relatively few cells (< 500 during gastrulation). The embryo is resilient to micromanipulation studies whereby cells or portions of tissues may be readily microinjected, transplanted, or photo-ablated to test mechanistically the crafting of the embryo. The whole genome project, its correlated EST identification and arrays (see http://sugp.caltech.edu), combined with the simple technology of introducing exogenous genes, reporters, mRNA, morpholinos or over-expressed proteins prove to be a powerful combination of capabilities with the nearly limitless number of embryos (several million per adult female) make the biochemistry and molecular biology of manipulated embryos readily available.[] Finally, its status as a basal deuterostome, representing an early branch in the evolution of vertebrates, makes its molecular and cellular changes ripe for comparison in understanding the origin of body plan, embryonic mechanism, gene regulation and function.

The sea urchin has been an instructive animal for studies of gene regulation in development, morphogenesis, and cell migration. This is in part due to their convenient external development, their ease in culturing, and their marvelous transparency that makes them optically accessible for many developmental and cellular events. The embryo displays a multitude of complex movements and features, but involves relatively few cells (< 500 during gastrulation). The embryo is resilient to micromanipulation studies whereby cells or portions of tissues may be readily microinjected, transplanted, or photo-ablated to test mechanistically the crafting of the embryo. The whole genome project, its correlated EST identification and arrays (see http://sugp.caltech.edu), combined with the simple technology of introducing exogenous genes, reporters, mRNA, morpholinos or over-expressed proteins prove to be a powerful combination of capabilities with the nearly limitless number of embryos (several million per adult female) make the biochemistry and molecular biology of manipulated embryos readily available.[] Finally, its status as a basal deuterostome, representing an early branch in the evolution of vertebrates, makes its molecular and cellular changes ripe for comparison in understanding the origin of body plan, embryonic mechanism, gene regulation and function.

The sea urchin has been an instructive animal for studies of gene regulation in development, morphogenesis, and cell migration. This is in part due to their convenient external development, their ease in culturing, and their marvelous transparency that makes them optically accessible for many developmental and cellular events. The embryo displays a multitude of complex movements and features, but involves relatively few cells (< 500 during gastrulation). The embryo is resilient to micromanipulation studies whereby cells or portions of tissues may be readily microinjected, transplanted, or photo-ablated to test mechanistically the crafting of the embryo. The whole genome project, its correlated EST identification and arrays (see http://sugp.caltech.edu), combined with the simple technology of introducing exogenous genes, reporters, mRNA, morpholinos or over-expressed proteins prove to be a powerful combination of capabilities with the nearly limitless number of embryos (several million per adult female) make the biochemistry and molecular biology of manipulated embryos readily available.[] Finally, its status as a basal deuterostome, representing an early branch in the evolution of vertebrates, makes its molecular and cellular changes ripe for comparison in understanding the origin of body plan, embryonic mechanism, gene regulation and function.